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MCL 显微定位C-Focus™ 系统
品牌MCL Think Nano
型号C-Focus™ System
同类产品(196件)
供应商报价

面议

所在地美洲 美国
北京欧兰科技发展有限公司

第1年

企业类型:国有
所在地:北京 海淀区

售全国

经营业务:
更新时间:2024-06-22 09:42:20
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MCL 显微定位C-Focus™ 系统技术参数
品牌 MCL Think Nano 型号 C-Focus™ System
MCL 显微定位C-Focus™ 系统详细介绍


Features
  • Microscope automatic focus drift correction

  • Interchangeable, quick mount adapters

  • 100 μm range of motion

  • Compatible with all microscopes

  • Closed loop control



Typical Applications
  • Maintain constant microscope focus

  • High speed confocal imaging

  • Ultra-fine focus adjustments

  • Drift correction


controller for microscope focus lock system
piezo stage and hardware for microscope focus lock systemdetail of front panel of controller for microscope focal drift correction system

Product Description

C-Focus systems provide an automatic means to eliminate microscope focus drift over long time periods. Unlike autofocus systems which require use of advanced microscopes with internal focus correction or external devices which track video signals or reflected laser beams, the C-Focus simply corrects for microscope focus drift by using a high resolution (5nm) sensor system to measure the lens/sample spacing and make the necessary adjustments. The C-Focus system has no effect on standard manual focusing and can be retrofit to any microscope. After focus is established, simply pushing the “focus lock” button starts the C-Focus operation. Objective lens motions are accomplished with a lens nanopositioner (the Nano-F100S) which is easily connected to the objective lens and microscope with standard threaded adapters. In addition to the unique C-Focus operation, lens nanopositioner motion can also be directly commanded by digital (16-bit USB) or analog signals and can be used for high speed, high resolution confocal imaging and other imaging tasks with demanding focus requirements. The C-Focus lens positioning system contains the same proprietary, low noise PicoQposition sensors used in the Nano-F100S and is capable of sub-nanometer positioning resolution. The 16-bit USB digital computer interface is included with all C-Focus controllers.



C-Focus Data

Set of Cy3 single molecule imaging
Sample: MutS protein imaged with Cy3 in presence of oxygen scavenging system
Technique: Prism TIRF
Microscope: Olympus IX71
Objective: 60x 1.2 NA Water Immersion, 1.6x magnification
Camera: Hamamatsu EMCCD

animation of performance of focus lock focal drift correction system

Courtesy of:
Biomolecular & Cellular Dynamics Lab
Dept of Physics/IBIO, POSTECH South Korea
http://jblab.postech.ac.kr




Focus Drift vs. Constant Focus

.microscope focal drift correction during comparing with and without focus lock engaged

plot of microscope drift versus focal position during a long duration experiment



Technical Specifications

Range of motion (Nano-F100)100 μm
Resolution0.2 nm
Resonant Frequency500 Hz ±20%
Stiffness1.0 N/μm
Recommended max. load*0.5 kg
Body MaterialAl and Brass
ControllerC-Focus
* Larger load requirements 首ld be discussed with our engineering staff.



Additional Information

Nano-F100 Drawing
piezo focusing stage drawing

C-Focus System
C-Focus focus lock drift correction catalog page



Related Products

  • Nano-CyteLC

  • Nano-F Series

  • Nano-F25HS

  • RM21 Microscope Platform

  • Accessories

  • Nano-Drive


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